Sandra was the name of a female bluepill who married a Goliath-like man in each of the two separate timelines the man was able to recall. The first time, when the man was living his life as a bookkeeper for a computer company, and the second time, when the man became a pilot after a déjà vu that rewound time within the Matrix years back, causing its inhabitants to also age back and allowing them to replay their lives.
When Sandra married the man the first time, they had two children that were both normal sized. But their marriage soon failed and she left her husband, taking their two children with her.
When the Machines wanted to turn the husband into a pilot, they rewound time within the Matrix years back. This also caused the RSI of everyone in it to grow younger, resetting the memories of those affected in the process. Her husband restarted back as a sixteen-year-old teen and, through time, Sandra once more dated and married the man but, this time, ended up having no children with him for fear of the children having a mutation. As if already having replayed through her life multiple times though, she carried out her life seemingly knowing that she was supposed to leave her husband. At some point, things grew tense with their marriage and she left to stay with her mother's, after which she never saw her husband again.
After another rewind within the Matrix, resetting to a point before Sandra married the man, they ended up no longer getting married.